Kerlin Lab
Neuroscience | University of Minnesota
Our Research
Publications
Dana H, Sun Y, Mohar B, Hulse BK, Kerlin AM, Hasseman JP, Tsegaye G, Tsang A, Wong A, Patel R, Macklin JJ, Chen Y, Konnerth A, Jayaraman V, Looger LL, Schreiter ER, Svoboda K & Kim DS (2019) High-performance calcium sensors for imaging activity in neuronal populations and microcompartments Nature Methods. 16:649–657
Lu R, Sum W, Liang Y, Kerlin A, Bierfeld J, Seelig J, Wilson D, Scholl B, Mohar B, Tanimoto M, Koyama M, Fitzpatrick D, Orger M & Na J (2017) Video-rate volumetric functional imaging of the brain at synaptic resolution. Nature Neuroscience. 20:620-628.
Liu R, Milkie DE, Kerlin A, MacLennan B & Ji N (2014) Direct phase measurement in zonal wavefront reconstruction using multidither coherent optical adaptive technique. Optics Express. 22:1619-28.
Andermann ML, Kerlin AM, Roumis DK, Glickfeld LL & Reid RC (2011) Functional specialization of mouse higher visual cortical areas. Neuron. 72:1025-1039.
Bock DD, Allen Lee WC, Kerlin AM, Andermann ML, Hood G, Wetzel AW, Yurgenson S, Soucy ER, Kim HS & Reid RC (2011) Network anatomy and in vivo physiology of a group of visual cortical neurons. Nature. 471:177-182.
Kerlin AM, Andermann ML, Berezovskii VK & Reid RC (2010) Broadly tuned response properties of diverse inhibitory neuron subtypes in mouse visual cortex. Neuron. 67:858-71.
Members
Principal Investigator
Assistant Professor
Affiliations
Department of Neuroscience Optical Imaging and Brain Science MDT
Education
Ph.D. Neurobiology, Harvard University
BA Neuroscience, Oberlin College
Google Scholar
Researcher
Affiliations
Department of Neuroscience
Education
BS Neuroscience, University of Minnesota
Google Scholar
Optical Engineer
Affiliations
Optical Imaging and Brain Science MDT
Education
Ph.D. Physics University of California
MS Physics, University of California
BS Astrophysics/Physics, University of Minnesota
Google Scholar
News
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Out now @eLife! Here we (@KMlab4brains) characterize and investigate a long-range inhibitory neuron that largely evaded prior description, but that seems to have an enormously powerful impact on CA1 and on its downstream projection targets. https://elifesciences.org/articles/46816 Check it out!
Tremendous advance in ability to functionally image large expanses of cortical neuron dendritic arbor at high spatio-temporal resolution in a behaving (deciding) mouse! Suggests coding of different patterns at discrete stretches of dendrite (~10-15µm). A thrilling read! https://twitter.com/KerlinAaron/status/1189623847668109313
Our work on dendritic activity during decision-making was published in @eLife today! Privilege working with @boazmohar, @svoboda314, and @nspruston
https://elifesciences.org/articles/46966
#spinevis looks awesome! I love that the links are embedded in the @elife paper. https://twitter.com/KerlinAaron/status/1189623847668109313
Our work on dendritic activity during decision-making was published in @eLife today! Privilege working with @boazmohar, @svoboda314, and @nspruston
https://elifesciences.org/articles/46966
This is a very important paper. Large dataset of dendritic imaging during a task, carefully analyzed. Dendritic calcium clusters/hotspots are in the tails of a complicated distribution, but can be seen with enough data and care. Cool microscope too! https://twitter.com/KerlinAaron/status/1189623847668109313
Our work on dendritic activity during decision-making was published in @eLife today! Privilege working with @boazmohar, @svoboda314, and @nspruston
https://elifesciences.org/articles/46966
Join our team
The Kerlin Lab is recruiting Graduate Students, Postdocs, and Research Technicians interested in advanced imaging techniques and the neurobiology of learning! We are seeking creative individuals with both technical (e.g., engineering, computer science) and biological interests. Multiple fully funded positions are available. Interested individuals are encouraged to send a CV to info@kerlinlab.org.
Contact us
The Kerlin Lab is a member of the University of Minnesota’s Medical Discovery Team for Optical Imaging and Brain Science, the Center for Magnetic Resonance Research, and the Neuroscience Department in Jackson Hall.
321 Church Street SE
Jackson Hall (Lab: 3-114) (Office: 4-155A)
Minneapolis, MN 55455